ABSTRACT
Fungal surgical site infections (SSIs) trend to increase in the recent decades. This study aimed at estimating the prevalence of fungal SSIs, and the time of occurrence of fungal SSIs at the Sourô Sanou University Hospital (SSUHC) in Burkina Faso. This study was carried out in two departments of the SSUHC. Samples of postoperative purulent secretions were collected from June to December 2019. Purulent secretions swabs at the surgical site were aseptically collected using sterile cotton swabs. Standard mycology, CHROMagar, agglutination latex test and immunological test were used to identify the different Candida species. A total of 39 postoperative patients were included in the study. The median age was 27 years and the majority of patients were women (74.4%). The probability of isolating fungal agents from the surgical site was 2.6% three days after surgery. This probability was 14.4% and 49.5% at one week and 12 days after the surgical intervention, respectively. A total of 8 (20.51%) fungal species, all belonging to the genus Candida were identified in the study. These species were Candida albicans (3), Nakaseomyces glabrata (2), Candida tropicalis (2) and Pichia kudriavzevii (1). This study showed that Candida spp. could be the cause of the occurrence of SSIs at the SSUHC in Burkina Faso. So, physician must integrate the fungal causes in the management of SSIs.

ABSTRACT
Scabies is a contagious skin infestation caused by Sarcoptes scabiei var. hominis. Human contamination occurs mainly through prolonged skin-to-skin contact with an infected person. The diagnosis of human scabies in case of co-morbidity with another chronic skin disease could be a real challenge. Here, we report an unusual and rare case of co-morbidity of crusted scabies with systemic lupus erythematosus in resource-limited setting treated successfully with a combination of medical treatments with lifestyle and dietary measures. This case also showed the diagnostic and management challenges in a setting where the health system presents some weaknesses.

ABSTRACT
Strongyloidiasis is a soil-borne disease caused by nematodes of the genus Strongyloides. The species most relevant to human health is S. stercoralis. The infection can persist for life if left untreated and occurs in various clinical forms, from asymptomatic to death. It mainly affects tropical and subtropical regions, with an estimated 370 million people affected worldwide, including Mexico. The life cycle of this parasite is complex, with free-living and parasitic stages. Infective filariform larvae penetrate intact skin, reach the lungs and are swallowed, developing in the intestine. Diagnosis is challenging and is based on the detection of larvae in biological samples, as well as serological and molecular tests. The main treatment is ivermectin, effective against adult forms, but multiple rounds may be necessary due to the autoinfectious cycle. Immunocompromised people are more susceptible to severe and disseminated infections. The lack of awareness and resources in endemic areas makes timely diagnosis and treatment difficult. Strongyloidiasis is a neglected disease, receiving less attention and funding for research and treatment development. To address it, efforts are required in education, improvement of the health infrastructure, research and prevention strategies.

ABSTRACT
Background: Malaria is common in regions like sub-Saharan Africa and South East Asia, where it results in millions of mortalities per year. Resistance to currently available antimalarials further compounds the problem. Drug combination has been demonstrated to be effective in overcoming resistance to antimalarials. This study aimed to assess the efficacy of the combination of Artemether/Lumefantrine (AL) and Doxycycline (DX) against Plasmodium berghei infection in mice. Methods: Thirty Adult Swiss albino mice were inoculated with the chloroquine (CQ)-sensitive P. berghei NK65 strain. The curative test involved oral administration of any of DX, AL, AL/DX, or Chloroquine (CQ) to mice with established infections, while the suppressive test was performed by treating mice shortly after parasite inoculation. Parasitemia levels were monitored using thin smears stained with Giemsa solution. Mean Survival Time (MST) was determined for each group. Results: In the curative test, DX, AL, and AL/DX exhibited parasitemia inhibitions of 81.4%, 94.5%, and 93.2%, respectively, while CQ achieved 93.5% inhibition. MST was significantly extended by DX, AL, and AL/DX treatments compared to negative control (NC). In the suppressive test, parasitemia inhibitions were 79.9%, 96.1%, 95.5%, and 94.9% for DX, AL, AL/DX, and CQ, respectively. The administration of DX, AL, and AL/DX also significantly prolonged MST compared to NC. Conclusion: The study demonstrates that the drug combination, particularly AL/DX, exhibits significant antimalarial effects in both curative and suppressive tests. The combination treatments led to substantial reductions in parasitemia levels and extended mean survival time, indicating their potential as effective antimalarial strategies. These findings highlight the promising role of drug combinations in addressing malaria infections and suggest avenues for further investigation and development of combination therapies.

ABSTRACT
Coccidiosis is an important enteric parasitic protozoan disease of poultry. The disease is usually associated with high economic losses to poultry farmers worldwide. This study was conducted to determine the prevalence of coccidiosis, identify the species of circulating Eimeria species, determine the prevalence of Eimeria in respect to breed and gender and determine the deviation of infected birds from normal range of birds slaughtered in Lafia modern market, Nasarawa State, Nigeria. Out of the 204 examined chickens, 36.3% (74/204) of them harbored different Eimeria species. A total of 32.6% (44/74) male and 43.5 (30/74) female were infected. Statistically, no significant difference p>0.05 (χ2=1.559, p=0.2118) was noted between the male and female. Among the local breed, 40.2% (49/74) was infected and for the broilers, 30.5% (25/74) was positive for coccidial infection. Again, there was no statistically significant difference p>0.05 (χ2=1.324, p=0.25) between the local and broiler breeds. In the attempt made to identify the prevalent species of coccidian in the study area, five Eimerian species were identified, namely; Eimeria acervulina, Eimeria brunette, Eimeria mitis, Eimeria necatrix and Eimeria tenella with the prevalence of 14.22%, 5.88%, 1.47%, 6.86%, and 7.84% respectively. Results obtained from this study shows that coccidiosis is an important disease of chickens in the study area and further strategy needs to be implemented to reduce the infection rate of coccidiosis.

ABSTRACT
Background: IT enabled medical services such as Telemedicine and e-health is fast developing from the recent past which supports long distance health care services. The term is often used as an umbrella term that includes tele-health, electronic medical records, e-health and other components of health information technology. Aim: To assess the knowledge, Attitude, Skills towards health care professionals. Methodology: In this descriptive cross sectional study, questionnaire‐based study among various levels of health care professionals at tertiary care centre, in ananthapuram district, Andhra Pradesh. The sample size was 177 by using convenient sampling method. The health care workers willing to fill the questionnaire were considered to have consented to the study. The same was mentioned at the start of the questionnaire. This study was carried out from December 2022 to February 2023. Results: Out of 177 health care professional’s 52% females and 48% males. Most of the subjects belongs to 25 to 30 years were 58%. Least of the subjects 3.95% has no about telemedicine application, 22.59% heard about telemedicine applications and 73.44 know about the telemedicine application. Only 33.89% are in learner stage and 29.94% are experts in email sending. Ability of Microsoft usage is 49.2 %, 31.6% and 19.4% in learner, mediocre and expert level respectively. Only 9.6% has no idea on patient management through telemedicine, 56.49% heard about patient management through telemedicine and 33.89% knew that patient management can be done through telemedicine. Conclusion: Most of the study subjects lack of knowledge and skills towards telemedicine. So, need of training programmes among health care professionals and proper guidelines by government.

ABSTRACT
Background: The organ donation in India was very low when compared to other countries. As the medical students were future health care professionals who were the first contact of potential donors family, the knowledge and attitude of medical students towards organ donation is of utmost important for the success of the organ donation program in a country. Objectives: This study aimed to assess the knowledge and attitude of medical students regarding organ donation at Government Medical College, Ananthapuramu, Andhra Pradesh, India. Methodology: This is a descriptive cross-sectional study, conducted among third year medical under graduate students of a Government Medical College between January to March 2023. Data was collected by structured, self-administered questionnaire from 141 third year MBBS students who were selected by convenient sampling. A structured, self-administered questionnaire consisting of 25 questions was used, which includes details on socio demographic characteristics, knowledge, attitude and practice towards organ donation. Results: The findings showed that a majority (90%) of the students had satisfactory knowledge regarding organ donation, 80% of the medical students expressed their willingness to donate their organs. Which implies there was a gap between knowledge and attitude. Conclusion: The study indicates that there is a need to introduce this topic into the curriculum, and by conducting frequent Continuing Medical Education (CME), they can become future donors and they motivate their patients, which can lead to an increase in organ donation rate.