ABSTRACT
Aim of the study: The purpose of this article is to report the experience of the General Reference Hospital in the surgical management of abdominal emergencies. Patients and Methods: This was a prospective study over 3 years 5 months (08/12/2017 to 31/05/2021) which concerned patients operated for an abdominal emergency at the General Reference Hospital of Niamey. Results: We had 170 patients operated for an abdominal emergency (8.37%), with a male predominance (61.50%) and a sex ratio of 1.59. The average age was 36.08 years with a standard deviation of 17.46 and extremes of 2 to 79 years. Non-traumatic abdominal emergencies dominated with 96.47%. Abdominal ultrasound was performed in 92.35% (n=157) of patients and abdominal CT scan in 35.88% (n=61). General anesthesia was performed in 97.06% of cases (n=165). The approaches were laparotomy in 72.35% (n=123) and laparoscopy in 27.65% (n=47). The most reported intraoperative diagnoses were acute appendicitis 40.59% (n=69) followed by acute peritonitis 18.82% (n= 32) and acute cholecystitis 13,53% (n= 23). The main procedures performed by laparoscopy were appendectomies, cholecystectomies and acute peritonitis in respectively 15.29%, 10.59% and 1.76% of cases. Postoperative complications represented 2.35% (n=4) in laparoscopy and 9.41% (n=16) in laparotomy. Conclusion: Abdominal emergencies at the Reference General Hospital are frequent and postoperative complications are few especially at laparoscopy, which is a first way to encourage in our context; It gives better surgical outcomes than conventional surgery.

ABSTRACT
Background: One of the world's major health problems, preterm labor is characterized by significant perinatal mortality and morbidity. In one of these clinical situations, a healthy pregnancy might become one that is at high risk for both the mother and the fetus. Objective: To detect the risk factors and perinatal outcome in with complication in preterm labor. Materials and Methods: A case control study was carried out from February 2010 to July 2010 in the department of gynecology and obstetrics at the Dhaka Medical College Hospital. Results: A total of 50 instances of preterm labor occurring between 28 and 36 weeks of pregnancy and 50 control cases of lobour pain occurring between 37 and 40 weeks of pregnancy were screened and recruited in the research. The following risk variables were identified as being significantly linked with premature labor. Preterm delivery (OR -9.33), and Anaemia (OR = 8.31). Perinatal outcome in preterm lobour were Still birth, low APGAR score, neonatal resuscitation and neonatal complications significantly (p<0.05) higher in case group. Conclusion: The purpose should be to raise awareness of pregnant women who are at high risk for preterm labor since preterm labor has serious repercussions for both the mother and the infant.

ABSTRACT
The nutritious jujube fruit (Ziziphus jujube Mill.) is a member of the Rhamnaceous family and grows mainly in inland areas of Europe, southern and eastern Asia, Australia and especially northern China. Jujubes have a long history as fruit and medicinal. The main bioactive components are vitamin C, phenols, flavonoids, triterpenoids and polysaccharides. Chlorogenic acid (5-O-caffeoylquinic acid) is a phenolic compound of the hydroxycinnamic acid family found in the hydroethanolic fruit extract of Z.jujuba. This polyphenol has many health-enhancing properties, most of which are relevant for the treatment of metabolic syndrome, including antioxidant, anti-inflammatory, antilipidemic, antidiabetic, and antihypertensive effects. Methods: Molecular docking of COX2 with chlorogenic acid was carried out by AutoDock. Result: The molecular docking result revealed that chlorogenic acid showed encouraging docking score. The docking score found to be -5.15.

ABSTRACT
Pólya thinks the major goal of teaching is to teach students how to ponder. It means that we need not only to give them the knowledge but also to help them improve their ability of using the knowledge and to help them form a good habit of thinking and a good mental state. He also thinks that what the teacher says in class is very important and what is more important is to learn what the students are thinking about. From this standpoint, he presents the three Learning Principles, which is also known as 3 Teaching Principles. These principles are quite practical and are worth practicing and improving in teaching. This article introduces how to use the principles, taking Interpolation Method for example.

ABSTRACT
Simulation-based learning (SBL) is a pedagogical method of teaching and assessing clinical skills across all levels of midwifery education. The SBL is based on implementing scenarios. The stages of a clinical scenario include briefing, action and debriefing. Briefing includes information to guide trainees on the scenario and the objectives. The training of participants in the clinical scenarios begins under the supervision of the instructors which is referred to as action. After each scenario, a debriefing takes place to provide immediate feedback on participants and their performance. Finally, an assessment of the trainees’ attitudes, skills and knowledge, is provided. The skills developed during simulation training are knowledge of algorithms, learning clinical skills and handling emergency situations, developing ethical values and decision-making, self-confidence and competence, communication with the patient and the colleagues, teamwork and leadership, patient safety and finally the satisfaction of being part of a multidisciplinary team. It is highly recommended that simulation is incorporated into midwifery curricula because it combines theory with practice and the development of specialized clinical skills to handle complex situations and get ready for future midwifery care.