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Postoperative peritonitis (POP) remains a severe complication of abdominal surgery, particularly in resource-limited settings, where delayed diagnosis and limited access to critical care contribute to poor outcomes. This study aimed to determine the prevalence, clinical characteristics, management modalities, and predictors of mortality among adults with postoperative peritonitis in Douala, Cameroon. We conducted a retrospective multicenter analytical study in two tertiary hospitals from January 2020 to December 2024. Adult patients diagnosed with postoperative peritonitis after abdominal or abdominopelvic surgery were included. Data were extracted from medical records and analyzed using univariate logistic regression. Among 4,763 laparotomies performed during the study period, 68 cases of postoperative peritonitis were identified, yielding a prevalence of 1.4%. After exclusion of incomplete records, 51 patients were included in the final analysis. The mean age was 35.4 ± 13.9 years, and women accounted for 82.4% of cases. Overall in-hospital mortality was 51.0%. The most frequent clinical features were abdominal pain (92.2%), abdominal guarding (86.3%), tachycardia (82.4%), and fever (76.5%). Deep suppuration (35.3%) and intestinal perforation (23.5%) were the most common intraoperative findings. Mortality was significantly associated with postoperative sepsis (OR 40.25, p<0.001), multiorgan failure (OR 37.84, p<0.001), vasopressor use (OR 17.60, p=0.002), prothrombin time <50% (OR 8.84, p=0.050), intensive care monitoring (OR 6.98, p=0.002), and blood transfusion (OR 4.55, p=0.020). Postoperative peritonitis remains an uncommon but highly lethal complication in our setting. Early diagnosis, prompt surgical source control, and

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Background: Temporary digestive stomas are frequently used in colorectal and emergency digestive surgery. Although digestive continuity restoration (DCR) improves quality of life and intestinal function, it remains associated with substantial postoperative morbidity. Data from sub-Saharan Africa remain scarce, particularly regarding predictors of adverse postoperative outcomes. Objective: To evaluate surgical practices, postoperative outcomes, and determinants of morbidity following digestive continuity restoration in three tertiary referral hospitals in Cameroon. Methods: A retrospective multicenter cohort study was conducted between January 2014 and December 2023 in three referral hospitals in Douala, Cameroon. Patients undergoing digestive continuity restoration after temporary digestive stoma formation were included. Sociodemographic, clinical, operative, and postoperative variables were analyzed. Factors associated with postoperative morbidity were identified using multivariable logistic regression. Results: Among 311 eligible patients, 264 were included in the final analysis. The mean age was 38.5 ± 18.7 years, and 55.7% were male. Infectious diseases (36.3%) and neoplastic conditions (26.1%) were the leading indications for temporary stoma creation. Colostomies accounted for 83.0% of all stomas. Peristomal mini-laparotomy was the most commonly used approach (59.1%). Overall postoperative morbidity reached 30.7%. Thirty-day mortality was 2.3%, while overall mortality during follow-up reached 5.7%. Previous stoma-related medical complications independently increased the risk of postoperative morbidity (aOR 4.64; 95% CI 2.16–9.97; p<0.001). ASA III status (aOR 3.45; 95% CI 1.40–8.47; p=0.007) and delayed restoration beyond 180 days (aOR 2.29; 95% CI 1.06–4.96; p=0.035) were also associated with increased morbidity. Conversely, the peristomal mini-laparotomy approach was protective (aOR 0.28; 95% CI 0.11–0.71; p=0.007). Conclusion: Digestive continuity restoratio

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Background: Post-mastectomy complications remain a major concern in patients with advanced breast cancer, particularly in low-resource settings where delayed diagnosis and advanced-stage presentation are common. This study aimed to identify factors associated with post-mastectomy complications among patients with advanced breast cancer in Douala, Cameroon. Methods: A multicenter cross-sectional analytical study was conducted in four reference hospitals in Douala from January 1, 2014, to December 31, 2023. A total of 523 patients who underwent mastectomy for histologically confirmed breast cancer were included. Sociodemographic, clinical, paraclinical, therapeutic, and postoperative data were collected using a structured form. Bivariate and multivariate logistic regression analyses were performed using SPSS software version 28.0. Statistical significance was set at p < 0.05. Results: The mean age of the patients was 47.0 ± 12.1 years. The most frequent post-mastectomy complications were lymphedema, anxiety, seroma, depression, pain, surgical site infection, sexual dysfunction, sensory disturbance of the arm, hemorrhage, and hematoma. In multivariate analysis, age 65–75 years, consultation delay of 6–9 months, invasive lobular carcinoma, and stage IIIb disease remained independently associated with post-mastectomy complications, whereas surgeon specialty lost statistical significance after adjustment. Conclusion: Advanced age, delayed consultation, invasive lobular carcinoma, and stage IIIb breast cancer were associated with post-mastectomy complications. Early diagnosis, timely surgical management, and multidisciplinary perioperative care may reduce postoperative morbidity and improve outcomes among patients with advanced breast cancer in Cameroon.

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Background: Cholangiocarcinoma (CCA) is the disease of public health importance due to the increase in number of cases in the last 30 years. Because of its late presentation of the disease has been associated with worse outcomes. Moreover, treatment options are limited due to the complexity of the condition. There are limited studies on the subject matter in our country; therefore, this study aims to assess factors influencing treatment outcomes among patients with cholangiocarcinoma treated from January 2017 to December 2021 at MNH. Results: This study that involved 108 case notes of patients with cholangiocarcinoma. Female patients were 57 and male 51. It was found that median age at diagnosis was 59. It was shown by using radiological imaging (CT scan and MRCP) that majority of patients had perihilar cholangiocarcinoma 76 (71%) followed by distal cholangiocarcinoma 20(18.7%). On metastasis 54(50%) patients had metastasis and the leading organ of metastasis being the liver 40 (74.1%). Only 46 were checked for CEA and 37 were checked for CA19-9 pre intervention and less than 5% post intervention. Study revealed that 9 (8.33%) patients were treated surgical. out of 73 patients, majority 63 (86.3%) patients had no complication after treatment, only 10 (13.7%) patients developed complications. Among 10 patients developed the following complications; peri-catheter leak after (PTBD) 4 (40%), anastomotic leak 2 (20%), SSI 1 (10%) and others (pulmonary embolism, catheter occlusion) 3 (30%) patients. Furthermore, out of 73 patients, the mortality of the patients post intervention were 7 (9.6%) patients. On factors associated with early treatment outcomes, it was revealed that; patients with more than 50 years 9 (15%), perihilar cholangiocarcinoma 8 (15.1%) and metastasis of the tumor 5 (16.1%) had complications. It was shown that there was no significant difference on factors associated with complication after intervention. Conclusion: This study concluded that there was n

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