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Introduction: The objective was to identify certain factors contributing to the poor prognosis of malignant tumours of the limbs. Materials and Methods: This is a descriptive cross-sectional study with retrospective data collection spanning eight years, conducted in the paediatric surgery department of Donka National Hospital. The parameters studied were epidemiological, diagnostic, therapeutic and evolutionary. Results: We collected 14 patient files of patients admitted, hospitalised, treated and followed up for malignant bone tumours of the limbs, including 12 cases of osteosarcoma and 2 cases of Ewing's tumour. The frequency of bone tumours compared to other tumours was 4.75%, with a clear predominance of osteosarcoma (85.71%). The average age was 12.5 years (7 to 17 years), with a sex ratio of 1.8. The average time between onset and consultation was 5.6 months (1 to 24 months). The reasons for consultation were dominated by pain and swelling of the limb in all patients. The mode of detection was traumatic fracture in 6 cases (42.86%). The tumour site was the distal femur in 8 cases (57.14%). The left pelvic limb was affected in 8 cases (42.86%). CT scans were performed in 11 cases (78.57%). Biopsies were performed in all patients. Amputation was performed in 8 patients. The 1-year Survival rate was 2 patients (14.28%). Conclusion: Malignant bone tumours of the limbs are a cause for concern due to delays in diagnosis and treatment. Multidisciplinary consultation involving the authorities and partners could improve treatment.

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Introduction: The aim of this study was to investigate the characteristics of patients admitted for acute leukaemia in paediatric oncology at Donka National Hospital. Methods: This was a retrospective and descriptive study. We extracted data from the GFAOP Redcap registry for patients admitted between 1 January 2019 and 31 December 2023 to the paediatric haematology and oncology unit at Donka National Hospital. Results: There were 331 confirmed cases of cancer and 96 cases of acute leukaemia, representing a frequency of 29%. Children aged 0–4 years were the most represented, with a male predominance and a sex ratio of 1.13. The socioeconomic status was low for 70.83% of patients. Acute lymphoblastic leukaemia accounted for 80.2% of patients. 90.62% of patients had already consulted a hospital before coming to the unit. There was a 96.87% mortality rate. Conclusion: Acute leukaemia in children is common at Donka National Hospital. Acute lymphoblastic leukaemia is the most prevalent form. Treatment is marked by high rates of loss to follow-up and mortality.

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Introduction: Epilepsy is a chronic disease with a very high prevalence in developing countries. While the links between alcohol and epileptic seizures are now well established, the clinical context of alcohol-related seizures remains debated. Several studies carried out in emergency departments and neurology wards have shown that alcohol use disorder (AUD) is associated with 40% to 50% of seizures observed in adult patients admitted for epileptic seizures, making AUD the main risk factor for seizures in adults. There are few epidemiological studies on the prevalence of epilepsy in patients with alcohol use disorder (PWAUD) and alcoholism in patients living with epilepsy (PWE). Objectives: We aimed to investigate the prevalence and aetiologies of epileptic seizures in chronic alcohol abusers in three Yaoundé referral hospitals over the last 10 years (January 2006 to December 2015). Methodology: A retrospective descriptive study was conducted on Cameroonian chronic alcoholics who presented at least one epileptic seizure and were hospitalised between January 2006 and December 2015 in the internal medicine units of three referral hospitals in Yaoundé. The sampling method was consecutive and exhaustive. Results: We obtained 250 chronic alcoholics aged between 25 and 89 years, with an average age of 54.26 ± 30.27 years. Eighty per cent consumed between 60 and 100g of alcohol per day. The prevalence of epileptic seizures in chronic alcoholics was 16.4%. The majority of seizures were generalised (61%), and mainly tonic-clonic (48.8%). The most common causes were infectious, with cerebral toxoplasmosis being the most frequent infectious aetiology (22%). Other aetiologies included toxic causes (alcohol withdrawal 17.1% and acute intoxication 7.3%); vascular causes (14.6%); traumatic causes (9.8%) and undetermined causes (9.8%). Conclusion: The prevalence of epileptic seizures in chronic alcohol abusers in Cameroon is very high. These seizures have various aetiologies and are

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High-degree atrioventricular (AV) block is a life-threatening emergency that may reveal an underlying infectious cause, such as a septal interventricular abscess. We report a case of a 22-year-old male admitted with recurrent syncopal episodes. Clinical evaluation revealed irregular bradycardia (42 bpm) and a grade 3/6 diastolic murmur at the aortic area. Electrocardiography confirmed high-degree AV block, necessitating temporary pacing. Multimodal imaging including transthoracic, transesophageal echocardiography and cardiac Computed Tomography identified an abscess-like collection within the interventricular septum, originating from the aortic valve. Laboratory findings supported systemic infection. Due to limited surgical capacity, the patient was managed conservatively with antibiotic therapy. He demonstrated clinical improvement, with regression of the abscess and resolution of conduction abnormalities to first-degree AV block, allowing removal of the temporary pacemaker. This case highlights the severity of infectious AV block and illustrates the diagnostic and therapeutic challenges faced in resource-limited settings.

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Background: Vaginal bleeding is the most common reason for consultation in early pregnancy and its effects on pregnancies that survive are still unclear. Objective: Our aim was to study the relationship between bleeding in the first half of pregnancy (BFHP) and foetal outcome (birth weight, gestational age at delivery, and 5th minute Apgar score) in a resource-limited setting. Methods: We conducted a retrospective cohort study in two hospitals in Yaoundé, Cameroon. Medical records of pregnant women who gave birth between January 2020 and May 2023 were reviewed. Participants were categorized into exposed (had vaginal bleeding <20 weeks of gestation) and unexposed groups. Foetal outcome (birth weight, gestational age at delivery, and Apgar score) was the primary outcome. Linear regression analysis was used to examine the contributions of variables to changes in foetal outcome. Results: Of the 200 women included, 35 (17.5%) experienced BFHP. The mean birth weight was significantly lower among women who bled compared to those who did not (2,813 ± 1,008g versus 3,276 ± 566 g; p <0.001). Similarly, the mean gestational age at delivery was smaller in the exposed group (36.3 ± 4.1 weeks versus 38.7 ± 2.4 weeks; p <0.001). The risk of low birth weight was nearly fivefold higher among women with BFHP (RR = 4.7; 95% CI: 2.4–9.3; p <0.001). Among women with BFHP, neither the duration (<1 day or >1 day) nor the gestational age at onset (<10 weeks or >10 weeks) influenced birth weight or gestational age at delivery. While regression analysis suggested a potential decrease in birth weight by 116 grams in the exposed group, this association was not statistically significant (p = 0.326). Conclusion: This study’s findings suggest significant contribution of BFHP, and a history of BFHP in a previous pregnancy, to low birth weight and prematurity. However, further research, with larger samples or a prospective approach, is needed to better elucidate this relationship and the need to an

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Introduction: The objective was to present the results of the management of traumatic pelvic fractures in children in the department. Materials and Methods: This is a prospective 16-month study from January 2024 to July 2025 on patients admitted, hospitalised and treated for traumatic pelvic fractures. The parameters studied were epidemiological, clinical, radiological, therapeutic and evolutionary. Results: Thirty patients were registered, corresponding to 35 cases of lower limb fractures. The average age was 11.7 years (7 to 15 years). There were 13 (43.33%) boys and 17 (56.67%) girls, with a sex ratio of 0.76. The majority of patients were schoolchildren (28, or 93.33%). Only five (16.66%) patients were transported by ambulance. Road traffic accidents accounted for 25 cases (83.33%). Pain associated with functional impairment was found in all cases. The fracture was closed in 21 cases (70%). Overlap was the most commonly observed displacement in 14 cases (40%). ECMES was performed in 16 cases (45; 71%). The average length of hospitalisation was 17.46 days (1 to 140 days). The outcome was favourable in 25 patients (80.33%). The minimum follow-up period was 6 months. Conclusion: Traumatic fractures of the lower limb are common in our setting, with schoolchildren being the most affected. Only prevention can help reduce the frequency of these accidents.