ABSTRACT
Dermatofibrosarcoma (DFS) is a fibrous tumor of the skin, slow growing, with a very high risk of local recurrence, but with a low metastatic potential associated with a specific chromosomal translocation. It is found more frequently in adults and the elderly. The curative treatment is surgical by a wide excision laterally and in depth. This excision results in large losses of substances, the coverage of which is a real challenge for the surgeon and requires different means ranging from skin grafts to free musculo-cutaneous flaps. We report the case of a 49-year-old patient with a voluminous purplish polylobed anterior and upper thoracic mass. The radiological assessment revealed a superficial parietal dermal mass. He had a biopsy confirming the diagnosis of Dermatofibrosarcoma of Darried and Ferrand. The excision surgery allowed a wide and complete resection with directed recovery with excellent postoperative results without recurrence at 06 months. The aim of this article is to present the therapeutic procedure for this pathology taking into account the site of the tumor, the size, the time of occurrence, the number of recurrences, the clinical signs, the operating protocol, the results of the pathological examination and post-operative complications with a review of the literature.

ABSTRACT
Isolated iliac artery aneurysms are extremely rare, accounting for less than 2% of all aneurysmal diseases. These aneurysms are usually seen in older men. Very mildly symptomatic but carries a significant risk of rupture when the aneurysms have reached a large size. Their operative mortality is significantly higher when undertaken as an urgent or elective procedure, highlighting the importance of early diagnosis and appropriate management. The development of radiological exploration methods has facilitated the discovery and diagnosis of these aneurysms. The emergence of endovascular techniques constitutes an alternative to traditional surgical treatment. We report our surgical management of an aneurysm of the primary iliac artery isolated in a 71-year-old man, who benefited in our department from a resection of the aneurysm with restoration of continuity by a prosthetic bypass. The objective of this article is to present and describe the diagnostic assessment; imaging data, treatment methods as well as a review of the literature concerning the history of iliac artery aneurysms.

ABSTRACT
Introduction: The sequelae of burns induce variable functional, aesthetic and psychological repercussions. They can be minor or major. The sequelae of burns are basically attributable to two causes: the male therapy conducted and the severity of the burn itself. Objective: To describe the clinical and epidemiological characteristics of burn sequelae in the "young" Dermatology Hospital of Bamako in Mali. Methodology: A descriptive and transversal study carried up on patients with burns sequelae and operated in Dermatological hospital of Bamako at the plastic and oncological service from January 2017 to December 2020. The study population consisted of all the patients (138 cases) with burns sequelae. Result: The sex ratio was 1.06. The mean age was 13.73 years (range: 7 months to 74 years). The most affected age group was paediatric with 65.90% of cases and the dominant age group was 0 to 5 years old with 41.3%. Hot liquid was the most frequently found causative agent at 52.9%, followed by fire and hot metal at 31.2% and 8%, respectively. Flanges were the most dominant (56.80%), followed by cupboards (33.73%) and ulcers on old burns (4.73%). Conclusion: A well-conducted therapy would not only reduce the severity of burn sequelae but also avoid them, which would allow empowering patients after burns and reducing the high costs associated with the management of these sequelae.

ABSTRACT
Giant lipomas are voluminous benign mesenchymal tumors formed by fatty lobules from mature adipose tissue and whose exact etiological is not yet elucidated. We report the case of a 64-year-old patient with a giant lipoma at the hip with physical and psychological impact. Treatment was surgical and consisted of a wide excision of the mass. The surgical piece measured 378X303 mm and weighed 2600 grams. The surgical follow-ups were simple. The late management of lipomas can lead them to reach an inordinate size causing disabilities and increasing the possibility of neoplastic transformation. After excision, a pathological anatomopatological study is required to rule out a liposarcoma.

ABSTRACT
Photodynamic treatment (PDT) has emerged as a promising therapeutic approach for immune system diseases due to its ability to selectively target abnormal cells while modulating the immune response. This review explores the mechanisms by which PDT activates the immune system to target diseased cells, including the induction of immunogenic cell death, activation of dendritic cells, release of tumor-associated antigens, modulation of immune checkpoints, and induction of cytokines and chemokines. Additionally, PDT can generate reactive oxygen species, induce apoptosis, and exhibit anti-inflammatory and vascular effects, all of which contribute to its therapeutic potential in immune system diseases [1]. Harnessing PDT for immune system diseases offers a unique opportunity to leverage the immune system's inherent ability to recognize and eliminate abnormal cells, providing a targeted and potentially less toxic treatment option. Further research and clinical studies are warranted to fully elucidate the potential of PDT in the management of immune system diseases and to optimize its clinical application.

ABSTRACT
Introduction: The demographic characteristics of cancer patients correlate with their awareness of diagnosis, prognosis, and the psychological distress associated with their condition. Objectives: The purpose of this study was to evaluate patients' knowledge of psychological distress, diagnosis, and prognosis who were presenting to the palliative medicine department of a tertiary hospital in Bangladesh. Methodology: This cross‐sectional study was conducted among 377 patients living with cancer attending the Department of Palliative Medicine, Bangabandhu Sheikh Mujib Medical University, Bangladesh from November 2021 and March 2022. Information on the clinical and sociodemographic aspects was gathered through a structured questionnaire and in-person interview, and the degree of distress was measured using a distress thermometer. After information was gathered, descriptive statistics were used to analyze it. Result: Approximately 16.2% of patients were unaware of their diagnosis, with two-thirds (68%) lacking awareness of prognosis. Over half (54.1%) reported significant distress. Gender, education, employment status, and head-and-neck cancer diagnosis were linked to diagnosis awareness, while educational level predicted prognosis awareness. Younger age, head-and-neck or hematological cancer diagnosis and lack of awareness regarding diagnosis and prognosis were associated with distress. Conclusions: Higher education and socioeconomic status correlate with patients' awareness of diagnosis and prognosis. However, distress remains higher among those unaware of prognosis.

ABSTRACT
The organisation of the evacuation referral system is an important strategy for reducing maternal and perinatal mortality in Mali. Objective: To study obstetric evacuations received in the gynaecology and obstetrics department of the "Major Moussa DIAKITE" referral health centre in Kati. Method: We conducted a cross-sectional, descriptive and analytical study. Data were collected retrospectively and prospectively over a 12-month period (from 1 January to 31 December 2020). Sampling was exhaustive and included all cases of obstetric evacuation received and managed on site during the study period. Results: Out of a total of 3050 deliveries, we received and managed 352 cases of obstetric evacuation, representing a frequency of 11.5%. The average age of the patients was 25 years, with extremes of 15 and 44 years, although the 20-34 age group was dominant, accounting for 73.6% of cases. The majority of evacuees were housewives (86.4%), married (92%), nulliparous and primiparous (52%). Dystocic labour was the most common reason for evacuation (51.1%), followed by ante-partum haemorrhage (13.4%). Nearly nine out of ten women evacuated came from Community Health Centres (89.8%) and the most common means of evacuation was by ambulance (52.1%). The average time from admission to the start of care was 26.5 minutes, with extremes of 3 and 50 minutes. Delivery by the vaginal route was carried out in almost eight out of ten cases (79%). Newborns were resuscitated alive (7.9%); stillbirths were fresh (3.7%) and stillbirths were macerated (06%). We recorded 2 cases of maternal death (0.6%) and the causes of maternal death were haemorrhage due to uterine rupture and eclampsia. Conclusion: The improved organisation of the evacuation referral system in our facility has improved the maternal and, above all, foetal prognosis of obstetric evacuations, but more needs to be done.