Carson McCullers was an American novelist, short story writer, dramatist, essayist, and poet. Her writings often centered on the lives of ordinary people who struggle both physically and mentally. Her writings generally portray the inner longings; she wants to protect her characters from loneliness, confusion, and frustration. Through her characters, McCullers depicts her early days struggle through her characters. As a young girl, McCullers faced many problems; she has three times suffered from heart attacks. Her characters are longing to wander for true love from any one of their surroundings. They are unable to get it and come to a state of loneliness. McCullers’s writings also attempt to reconnect the emotional and physical conflicts of common people. She has explored her character's confusion and loneliness in her novel. Her characters attempt to make various conscious efforts to overcome the problem of the people and to get betterment in their lives. This paper mainly focuses on how McCullers's novel The Member of the Wedding highlights the theme of isolation and loneliness and how her characters are struggling in a small town is about primitive religion, adolescent hope, the silence of deaf-mutes, and all of these give the violent colures of the life. It is also focused on spiritual isolation and loneliness as the human condition in modern times, and her identification and compassion for the underdogs and outcasts of society.