This study aims to analyze the implementation of Presidential Regulation Number 44 of 2017 through cross-agency coordination at the Yetetkun Cross-Border Post (PLBN), Boven Digoel Regency, South Papua Province. PLBN Yetetkun has a strategic position as a service and supervision hub for the Indonesia-Papua New Guinea cross-border, involving various agencies with different functions and authorities. This study uses a qualitative approach with a case study design. Data were obtained through in-depth interviews, observations, and documentation of PLBN managers, technical agencies, local governments, and border communities. Data analysis used the interactive model of Miles, Huberman, and Saldaña, which includes data condensation, data presentation, and drawing and verifying conclusions. The main analysis used the Edwards III policy implementation model, which includes communication, resources, disposition, and bureaucratic structure. The results show that cross-agency coordination at PLBN Yetetkun has been running through operational communication, information exchange, division of tasks, and the implementation of relatively clear service procedures. Commitment of implementers and harmonious working relationships are supporting factors for implementation. However, obstacles remain, including limited personnel, unstable communication networks, limited facilities, geographical conditions, the absence of permanent police personnel, and suboptimal formal coordination. The study concluded that the effectiveness of policy implementation at the Yetetkun PLBN depends heavily on the ability to integrate communication, resources, implementer commitment, and institutional structure into ongoing operational coordination.