Background: Dental wear is a multifactorial condition characterized by the progressive and irreversible loss of dental hard tissues due to attrition, abrasion, erosion, or a combination of these processes. Although commonly associated with aging, increasing evidence suggests that dental wear may have important consequences beyond structural tooth loss, affecting oral function, aesthetics, and overall well-being. Objective: To review the available scientific evidence regarding the relationship between dental wear and oral health-related quality of life (OHRQoL) among adult populations and to discuss its clinical implications for patient-centered dental care. Review Findings: Current evidence indicates that dental wear may negatively influence multiple dimensions of oral health-related quality of life. Functional limitations, dentin hypersensitivity, masticatory difficulties, aesthetic concerns, and psychological discomfort have been identified as factors that may affect patients' perceptions of oral health and well-being. Patient-reported outcome measures, particularly the Oral Health Impact Profile (OHIP), have become valuable tools for assessing the broader impact of dental wear beyond traditional clinical indicators. Conclusion: Dental wear should be recognized not only as a clinical condition involving the loss of dental tissues but also as a factor that may influence quality of life. The incorporation of patient-centered assessments into routine dental practice may contribute to a more comprehensive understanding of the impact of dental wear and support preventive and therapeutic strategies aimed at improving oral health outcomes and overall well-being.