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Fitz-Hugh-Curtis Syndrome Mimicking Biliary Disease in Tanzania; A Case Series

DOI : https://doi.org/10.36349/easjms.2026.v08i03.009
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Introduction: Fitz-Hugh-Curtis Syndrome (FHCS) is a rare complication of pelvic inflammatory disease (PID) characterized by inflammation of the liver capsule and peritoneum, often resulting from chlamydial or gonococcal infections. Although it typically presents with right upper quadrant (RUQ) pain, its diagnosis can be challenging due to its similarity to other gastrointestinal or hepatic disorders. Understanding FHCS and its associated risk factors is crucial for timely diagnosis and management. Case 1: A 38-year-old female presented with episodic RUQ and epigastric pain over several months, unresponsive to medical treatment. Ultrasound showed gallstones, during laparoscopic cholecystectomy revealed violin-like adhesions on the liver, suggestive of FHCS. The patient had a history of multiple chlamydial infections and post surgery she became symptom free. Case 2: A 32-year-old woman with persistent RUQ pain, worsened by cold weather, underwent diagnostic laparoscopy revealing violin-like adhesions over the liver confirming FHCS. She underwent adhesiolysis and improved without further complications. Case 3: A 30-year-old female with symptomatic cholelithiasis and recurrent RUQ pain underwent laparoscopic cholecystectomy. During surgery, violin-like adhesions were noted, suggestive of FHCS. She underwent adhesiolysis and cholecystectomy with complete symptom resolution. Clinical Discussion: Fitz-Hugh-Curtis Syndrome is often underdiagnosed and can mimic other conditions like gallbladder disease or gastrointestinal disorders. Early diagnosis through imaging and laparoscopic evaluation is essential. Treatment may involve involves surgical intervention via adhesiolysis. Conclusion: FHCS should be considered in women with unexplained RUQ pain and a history of PID or sexually transmitted infections. Early surgical intervention led to successful outcomes with symptom resolution.

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Professor Thomas Count Dracula, MD, PhD

Distinguished Professor of Haematology Head — Experimental, Historical & Sensory Haematology Vlad the Impaler University, Wolf’s Lane, Wooden Stakes Grove 666, Transylvania.

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