Heart attacks, strokes, and sudden cardiac death can be avoided by routinely evaluating the cardiopulmonary profile, which includes the integrated function of the heart, lungs, and vascular system. Thus, the present study evaluated the cardiopulmonary profiles of traditional and industrial bread bakers resident in Port Harcourt. The present study adopted the survey-based cross-sectional approach to evaluate the cardiopulmonary profiles of traditional and industrial bread bakers resident in Port Harcourt. The quantitative data obtained from the study were statistically analysed using version 25.0 of the IBM Statistical Product and Service Solutions (SPSS) software. The present found that the age of the bakers and their non-baker counterparts ranged from 36.8 to 39.70 years; thus, implying a relatively young set of people make up the workforce in the bread baking industry. On BMI changes, the stud noted that the industrial bakers had significantly (p<0.05) elevated level when compared to those of non-bakers and traditional bakers. Only On the blood pressure profile, systolic blood pressure (SBP) of the bakers did not vary significantly (p>0.05), it was recorded here that, the value for the traditional bakers was the most marginally raised. The ECG findings on the bakers in the present study revealed that 60% of each of the traditional and industrial bakers presenting with sinus rhythm with abnormal findings ranging from left axis deviation, left/ or ventricular hypertrophy, incomplete right bundle branch block, left axis, deviation to clockwise QRS rotation. On the pulmonary profile screening, the mean FVC, FEV1 and FEV6 levels showed significant (p<0.05) reduced in the bakers. The traditional bakers even had much more significantly (p<0.05) lower levels of the parameters when compared to those of the industrial bakers. Thus, the bakers may need health education on the use of personal protective equipment and good health seeking behaviours to avert cardiopulmonary cri