Background: Long-distance commuting has become increasingly prevalent in urban environments and may negatively influence occupational balance and psychological well-being among employees. Objective: To explore the impact of frequent long-distance travel on occupational balance and psychological well-being among employees. Methodology: A cross-sectional observational survey was conducted among 50 employees aged 30–60 years who travelled ≥1 hour daily, 5 days per week. Participants were selected using purposive sampling. The Occupational Balance Questionnaire (OBQ-11) and WHO-5 Well-Being Index were administered. Data were analyzed using descriptive statistics and Pearson correlation. Results: The mean travel duration was 107.70 ± 26.65 minutes. The mean OBQ-11 score was 19.86 ± 2.66, and the mean WHO-5 score was 16.70 ± 3.27. A moderate positive correlation was observed between OBQ-11 and WHO-5 scores (r = 0.539, p < 0.01). Travel duration demonstrated a moderate negative correlation with OBQ-11 scores (r = –0.408, p < 0.01) and a strong negative correlation with WHO-5 scores (r = –0.801, p <0.01). Conclusion: Increased commuting duration is significantly associated with reduced occupational balance and psychological well-being among employees.