About Us   |   Contact Us   |  
Submission  

Clinical Profile, Management, and Outcomes of Breast Carcinoma with Spinal Metastases: A Cross-Sectional Study

DOI : https://doi.org/10.36349/easms.2022.v05i11.003
PDF
HTML
XML

Background: Breast carcinoma is the most common malignancy among women worldwide, and skeletal metastases represent a major cause of morbidity in advanced disease. The spine is the most frequent site of bone metastasis, often resulting in pain, neurological deficits, and mechanical instability. Optimal management requires a multidisciplinary approach integrating systemic therapy, radiotherapy, and surgical intervention tailored to disease burden and patient functional status. Objectives: To evaluate the clinical profile, management strategies, and outcomes of breast carcinoma patients presenting with spinal metastases. Methods: A cross-sectional study was conducted from July 2021 to December 2021 including 450 patients with histologically confirmed breast carcinoma and radiologically proven spinal metastases. Clinical features, radiological findings, management modalities including systemic therapy, radiotherapy, and surgery and outcomes were analyzed. Results: Multimodal management was employed in the majority of patients. Combined systemic therapy and radiotherapy constituted the most common treatment approach, while surgical intervention was reserved for patients with spinal instability or neurological compromise. Significant improvement in pain and neurological function was observed in patients receiving individualized, multidisciplinary management. Conclusion: Early diagnosis and evidence-based multimodal management significantly improve functional outcomes and quality of life in breast carcinoma patients with spinal metastases.

TOP EDITORS

OPEN ACCESS JOURNALS

Professor Thomas Count Dracula, MD, PhD

Distinguished Professor of Haematology Head — Experimental, Historical & Sensory Haematology Vlad the Impaler University, Wolf’s Lane, Wooden Stakes Grove 666, Transylvania.

BEST AUTHOR

Of The Month

TRACK YOUR ARTICLE

Enter the Manuscript Reference Number (MRN)
Get Details

Contact us


EAS Publisher (East African Scholars Publisher)
Nairobi, Kenya


Phone : +91-9365665504
Whatsapp : +91-8724002629
Email : easpublisher@gmail.com

About Us


EAS Publisher (East African Scholars Publisher) is an international scholar’s publisher for open access scientific journals in both print and online publishing from Kenya. Its aim is to provide scholars ... Read More Here

*This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2020, All Rights Reserved | SASPR Edu International Pvt. Ltd.

Developed by JM