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Factors Contributing to Poor Prognosis in Malignant Bone Tumours in the Paediatric Surgery Department of Donka National Hospital

DOI : https://doi.org/10.36349/easjms.2026.v08i02.003
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Introduction: The objective was to identify certain factors contributing to the poor prognosis of malignant tumours of the limbs. Materials and Methods: This is a descriptive cross-sectional study with retrospective data collection spanning eight years, conducted in the paediatric surgery department of Donka National Hospital. The parameters studied were epidemiological, diagnostic, therapeutic and evolutionary. Results: We collected 14 patient files of patients admitted, hospitalised, treated and followed up for malignant bone tumours of the limbs, including 12 cases of osteosarcoma and 2 cases of Ewing's tumour. The frequency of bone tumours compared to other tumours was 4.75%, with a clear predominance of osteosarcoma (85.71%). The average age was 12.5 years (7 to 17 years), with a sex ratio of 1.8. The average time between onset and consultation was 5.6 months (1 to 24 months). The reasons for consultation were dominated by pain and swelling of the limb in all patients. The mode of detection was traumatic fracture in 6 cases (42.86%). The tumour site was the distal femur in 8 cases (57.14%). The left pelvic limb was affected in 8 cases (42.86%). CT scans were performed in 11 cases (78.57%). Biopsies were performed in all patients. Amputation was performed in 8 patients. The 1-year Survival rate was 2 patients (14.28%). Conclusion: Malignant bone tumours of the limbs are a cause for concern due to delays in diagnosis and treatment. Multidisciplinary consultation involving the authorities and partners could improve treatment.

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Professor Thomas Count Dracula, MD, PhD

Distinguished Professor of Haematology Head — Experimental, Historical & Sensory Haematology Vlad the Impaler University, Wolf’s Lane, Wooden Stakes Grove 666, Transylvania.

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