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A Prospective Analysis of Patients with Surgical Jaundice: Clinical and Investigative Correlations

DOI : https://doi.org/10.36349/easjms.2026.v08i01.006
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Introduction: Surgical jaundice, or obstructive jaundice, results from the blockage of bile flow due to benign or malignant conditions, leading to elevated bilirubin levels and associated symptoms. Early identification of the underlying cause is crucial for timely intervention and improved patient outcomes. This study aimed to evaluate the clinical aspects of surgical jaundice in patients admitted to DMCH. Methods: This prospective observational study was conducted at the Department of Surgery, Dhaka Medical College Hospital, over 12 months. A total of 100 patients were selected as study subjects by purposive convenient sampling technique. The diagnosis was established based on investigations. After data collection, all entries were checked for consistency and analyzed using SPSS version 26. Result: Among 100 patients with surgical jaundice (mean age 53.7±10.9 years), 57% had malignant causes, primarily carcinoma of the pancreatic head (32%), while 43% had benign causes, with choledocholithiasis (28%) being the most common. Jaundice was universal, and abdominal pain was the most frequent symptom, though malignancy was significantly associated with loss of appetite, weight loss, dark urine, and abdominal lump (p<0.05). Liver function tests showed significantly higher serum bilirubin and alkaline phosphatase levels in malignant cases (p<0.001). Conclusion: This study found that carcinoma head of the pancreas and choledocholithiasis are the most common causes of surgical jaundice. Overall, malignancy is the most frequent etiology of surgical jaundice. Abdominal pain was the most common clinical presentation in both malignant and benign cases. Loss of appetite and weight, dark urine, and a lump in the abdomen were found significantly higher among the malignant jaundice patients than in benign cases.

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Professor Thomas Count Dracula, MD, PhD

Distinguished Professor of Haematology Head — Experimental, Historical & Sensory Haematology Vlad the Impaler University, Wolf’s Lane, Wooden Stakes Grove 666, Transylvania.

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