Background: Right colon surgery is a substantial component of digestive surgery in sub-Saharan Africa, where late presentation and emergency conditions remain frequent, and multicenter data are scarce. Objective: To describe the indications, surgical procedures and postoperative outcomes of right colon surgery in four referral hospitals of Douala, Cameroon. Methods: We conducted a retrospective descriptive multicenter study over 10 years (January 2012–December 2021). All patients aged ≥15 years who underwent right colon surgery were eligible. Sociodemographic, operative and postoperative variables were extracted from medical records and analyzed descriptively. Results: A total of 145 patients were included. Mean age was 46.16 ± 18.06 years (16–87), with male predominance (64.1%; sex ratio 1.78). Emergency surgery accounted for 67.58% of cases. Obstructive right colon cancer was the leading indication (25.51%). Right hemicolectomy was the most frequent procedure (57.24%). Overall postoperative morbidity was 65.51%, dominated by surgical site infections (35.06%) and enterocutaneous fistulas (25.97%). In-hospital mortality was 6.89% (n=10). Conclusion: Right colon surgery in Douala is mainly performed in emergency settings for advanced colorectal cancer and is associated with high morbidity. Strengthening early diagnosis and perioperative quality improvement is essential to improve outcomes.