Ultrasound is one of the methods proposed by researchers to investigate paranasal sinus disease conditions like rhinosinusitis. This method, unlike Computed Tomographic (CT) scan, does not involve exposure to radiation, and it is cost effective. Moreover, an ultrasound scan is safe, readily available, and non-invasive compared to the sinus puncture method, and it is easily accepted by patients. However, there is no enough information on the utilization and accuracy of this method in the diagnosis of maxillary sinusitis. The aim of this review is to investigate and elaborate on the role of ultrasound scan in the diagnosis of maxillary sinusitis. We conducted a comprehensive literature search across multiple research databases, including PubMed, Scopus, Web of Science, Google Scholar, Embase, EBSCO and Cochrane database. The result indicated that both A-mode and B-mode ultrasound scans were accurate in the diagnosis of maxillary sinusitis, with excellent sensibility, specificity, positive and negative predictive values compared with Magnetic Resonant Imaging (MRI), CT scan and sinus endoscopy. Therefore, we recommend the use of ultrasound scan for the diagnosis of maxillary sinusitis, especially in our environment where there are factors that limit the utilization of CT scan and MRI (such as repeated breakdown of the machines, high cost, and lack of good electricity).