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Pharmacognostical & Tlc Fingerprinting of Kiratatikta

DOI : https://doi.org/10.36349/easjpp.2019.v01i06.008
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Standardization plays crucial role for the selection proper raw materials in the production of herbal formulation. Swertia chirata has been used in traditional and folklore medicine for the treatment of several critical diseases and disorders. The present study was focused on preliminary pharmacognostic and phytochemical investigations for determining and establishing the identity, purity and quality of the plants. This will endow with an appropriate guidance for future exploration. The plant was subjected to determination of various physicochemical parameters including ash values (total ash, water soluble ash) and extractive values (alcohol soluble extractive, water soluble extractive). The powdered crude drug was extracted successively with various solvents with increasing polarity and further the extracts were subjected to phytochemical screening for the identification of various phytoconstituents. More over the fingerprint profile of Swertia chirata was established using thin layer chromatography(TLC) methods. TLC was carried out Toluene, Ethyl Acetate: Formic acid [5:4.5:0.5] as a solvent systems, which showed different Rf value. The results of the TLC profiling of the extract confirm about the presence of various phytochemicals.

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Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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