EAS Publisher | Preformulation Studies of Metoclopramide Hydrochloride: Fundamental Part of Formulation Design

Preformulation Studies of Metoclopramide Hydrochloride: Fundamental Part of Formulation Design

DOI : https://doi.org/10.36349/easjpp.2019.v01i06.007

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Preformulation study is a part which is initiated once the new molecule is seeded. In a broader way, it deals with studies of physical, chemical, analytical, and pharmaceutical properties related to molecule and provides idea about suitable modification in molecule to show a better performance. Preformulation parameters study can be associated to generation of effective, safer, stable, and reliable pharmaceutical formulation. Metoclopramide is used to enhance GI motility, to treat diabetic gastro-paresis, as an anti-nauseated, and to facilitate intubation of the small bowel during radiologic examination. Metoclopramide may be used to treat chemotherapy-induced emesis and as a radiosensitizing agents in the treatment of non-small cell lung carcinoma and glioblastomas in the future. In the present works overall objective of preformulation studies of Metoclopramide HCl is to engender information useful in developing stable and Bioavailable dosage forms.

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