EAS Publisher | Effect of Zinc on Spermatogenesis

Effect of Zinc on Spermatogenesis

DOI : https://doi.org/10.36349/easjpp.2019.v01i06.003

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Objective: To study the effect of zinc on spermatogenesis in albino rats.Method: This study was conducted in the Department of Pharmacology BMSI, JPMC Karachi. four groups of albino rats were made 15 rats in each group .Group one was control group given normal diet only , group two was given indomethacin, group three was given zinc and group four was given combination of Zinc and indomethacin. Drugs were given for 12 weeks. At the end of study histopathology of testes was performed to see spermatogenesis. Data was analyzed statistically.Results: In group 2 focal loss of normal distribution of germ cells series was seen with focal detachment of basement membrane.In group 4normal series of spermatogenesis seen Conclusion: Zinc has a protective role on testes.

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