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Spinal Anaesthesia With 0.5% Hyperbaric Ropivacaine and 0.5% Hyperbaric Bupivacaine: A Comparative Study

DOI : https://doi.org/10.36349/easjacc.2020.v02i03.008
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One of the primary aims of anaesthesia is to render adequate pain relief, thereby permitting the performance of surgical procedures without stress and discomfort. General anaesthesia does not abolish the stress response completely. The local anaesthetics when used intrathecal or epidural, abolishes the response to a great extent, particularly in lower abdominal operations. The present study designed to compare the clinical efficacy of hyperbaric solution of Ropivacaine (0.5%) with that of hyperbaric Bupivacaine (0.5%) in spinal anaesthesia.The aims and objectives of this study were to study the characteristics of spinal blockade in terms of sensory and motor blockade (onset, extent, regression and duration), hemodynamic stability, the recovery profile and side effects of both the drugs if any. In present randomized double blind prospective comparative study, after approval of ethical committee, 100 patients of either sex, ASA grade I and II, aged 20 – 60 years scheduled for different surgical procedures on abdomen, genitourinary region and lower extremity were included in this study. The sample size was determined by power analysis. The patients were randomly allocated into two groups. Pre-anaesthetic evaluation was done one day prior to surgery and all necessary investigations done. An informed consent was taken. Group R - Received inj. Ropivacaine 3 ml of 0.5% hyperbaric (in glucose 8.3%) solution. Group B - Received injection Bupivacaine 3 ml of 0.5% hyperbaric (glucose 8%) solution. Following observations were made - Time of onset of sensory block, maximum cephalic spread (dermatome), time to maximum cephalic spread, two segment regression time (min) and total duration of sensory block. Degree of motor block was assessed by Bromage scale. Intraoperatively, pulse rate, systolic and diastolic blood pressure, respiratory rate and SPO2 monitored at induction, 2, 5, 10, 15, 20, 25, 30, 45, 60 min with help of multipara monitor. In this study, for quantitative data o

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Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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