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A Retrospective Analysis of Outcome in Dengue Patients Admitted into a Multidisciplinary ICU of a Tertiary Care Teaching Hospital

DOI : https://doi.org/10.36349/easjacc.2020.v02i03.005
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Introduction :World wide dengue has become the most common vector bone tropical fever spread by Aedes Egypti.This virus have four circulating serotypes worldwide .In urban and suburban areas of high endemicity this infection is responsible for high mortality and morbidity.WHO estimates incidence of dengue globally ranges between 50 million to 200 million every year.Dengue fever presentations can vary from fatigability and malaise to severe shock and multiorgan dysfunction syndrome Methods All patients had a full work up for fever that included three smears for malarial parasites, serology for dengue, leptospirosis, scrub typhus, enteric fever, blood, urine,sputum or endotracheal cultures and other tests as clinically indicated.A diagnosis of Dengue was made when a patient is tested positive for NS1-Antigen Strip® ELISA (BioRad), IgM and IgG- Capture ELISA Panbio® (AlereTM) and other causes of fever excluded. Patients were treated with Ceftriaxone along with enteral doxycycline and intravenous azithromycin as needed. Results Of total patients,the vasopressor requirements being Dopamine(12.9%) , Nor adrenaline(12.9%) & Vasopressin(3.2%).1.6% received packed red blood cell transfusions whereas 80.6% had platelet transfusions . 4.8% required Non invasive ventilation whereas 9.7% required Invasive mechanical ventilation and 3.2% required both non invasive and invasive mechanical ventilation . 6.5% of patients had received haemodialysis.The mean duration of ICU and hospital stay were 4.25 and 6.54 days respectively. In hospital mortality was 1.6%. Conclusion In our study we hereby conclude the incidence of clinical features is in agreement with other studies whereas the in hospital mortality was relatively low.

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Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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