Low socioeconomic status, sub-standard housing, poor environmental conditions, limited access to healthcare facilities among other factors; are major urban risk factors that have implications on malaria epidemiology. Identifying the causal factor of malaria incidence and transmission in our urban areas is vital for sustainable integrated malaria control programs. Thus, this paper aims at analyzing the bionomics of malaria vector in Osogbo-a rapidly growing urban area and identifying the underlying urban risk factors causing malaria morbidity and transmission using geospatial analysis techniques. Focusing on the aim, the study was based on self-reported malaria cases from the dwellers using structured questionnaire forms; as well as data on the number of clinical reports and residential locations of malaria patients collected from LAUTECH Teaching Hospital and State Hospital, Asubiaro, Osogbo. The data was georeferenced and integrated into a Geographic Information System (GIS) to perform spatial hotspot analysis and proximity studies. Pearson correlation analysis was carried out on geospatial data obtained to determine the spatial association of the surveyed risk factors to malaria incidence. Results gathered reveal the spatial clustering of urban malaria in peri-urban and urban areas of Osogbo. Poor environmental condition in the form of pool of stagnant water (potholes in unpaved roads, water in abandoned containers, and rainwater in abandoned tyres) within or near household significantly correlated with malaria incidence when mapped using spatial interpolation techniques. These environmental factors were identified through spatial analysis as the risk factors serving as the major breeding points for malaria vectors causing febrile condition for the dwellers. Hence, effective environmental management programs guided by GIS-based surveillance is recommended as an essential feature in the sustainable alleviation of malaria burden in Osogbo and other urban areas in Ni