EAS Publisher | Ticagrelor as a Unique Antiplatelet Drug for Management of Covid-19 Infected People with a Hyperviscosity Syndrome

Ticagrelor as a Unique Antiplatelet Drug for Management of Covid-19 Infected People with a Hyperviscosity Syndrome

DOI : https://doi.org/10.36349/easjacc.2020.v02i02.007

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The whole world agrees on the significance of finding a vaccine or a drug that will aid in the eradication of the novel SARS-COV-2 infection, this extremely contagious virus has gained the characteristic of being pandemic according to the world health organization, in addition to its reputation as a virulent and notorious virus that has succeeded to position the humanity in a critical situation in many settings as financial, political and health-wise. When taking the new theory of COVID-19 pathogenesis into consideration, which is “radical storm- hyperoxidative” in combination with “cytokine storm hyper-inflammatory status”, we need to think of a drug that effects on both mechanisms of the pathogenesis. This dissertation investigates the potentiality of antiplatelet agents specifically Ticagrelor (due to its antiviral characteristics) rather than other agents in decreasing the hyper-viscosity syndrome complication of COVID-19, and reduce the patient's transformation to further late-stage issues such as disseminated intravascular coagulopathy (DIC) that is a direct way for death.

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Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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