This research aims to analyze the influence of information system effectiveness, employee training, and managerial support on employee performance, both directly and through the mediation of employee capability, at the Consumer Cooperative of Employees of the Republic of Indonesia at RSUD Dr. Saiful Anwar (KKPRI RSSA Syaiful Anwar). Using a quantitative approach and path analysis, data were collected from 50 employees who directly interacted with the information system through questionnaires. The results revealed that information system effectiveness, employee training, and managerial support significantly influence employee capability and performance. Employee capability was proven to mediate the relationship between these variables and employee performance. Information system effectiveness showed a stronger direct impact on performance than its indirect effect through employee capability. Conversely, employee training had a negative direct impact on performance but became positive when mediated by employee capability. This study highlights the importance of enhancing employee capability to support optimal performance through effective information systems, managerial support, and relevant training.