Adolescence is a phase of transition from childhood to adulthood. During this period that the adolescents acquire sexual and reproductive maturity. Health education given to adolescent girls helps build their knowledge, motivates them to improve and maintain their health, prevent diseases and reduce risky behaviours among them hence the study was done to assess the effectiveness of health education among rural adolescent girls. This study evaluated the efficacy of a reproductive health awareness program for adolescent girls in Bangalore, addressing critical topics like menstrual health, hygiene, and reproductive wellness. Using a pre-experimental one-group pre-test post-test design, the research involved 100 college-going girls selected through non-probability convenient sampling. Pre- and post-test assessments were conducted using a validated knowledge questionnaire. Results showed a significant improvement in knowledge scores, with mean scores increasing by 23.1 (t = 33, p < 0.001), indicating a shift from inadequate to adequate understanding. Demographic factors, such as class, religion, and menstrual regularity, were correlated with knowledge levels. The study concluded that the awareness program effectively enhanced the knowledge of adolescent girls, underscoring the need for continued health education initiatives. These findings suggest that such programs are vital for empowering young women and improving their reproductive health awareness, ultimately contributing to better health outcomes in this demographic.