Odontogenic perimandibular cellulitis are infections spreading into the celluloadipose tissues of the compartments of the perimandibular region. Promoted by taking non-steroidal anti-inflammatory drugs. They constitute an emergency for patients and especially pregnant women, because they are the cause of serious complications, which can endanger the maternal-fetal prognosis. To study the contributing factors, complications and management of odontogenic perimandibular cellulitis in pregnant women. Patients and method: This is a retrospective, descriptive and single-center study, focusing on patients hospitalized in the CMF Stomatology department from April 2022 to April 2024. The sources of information were the department registers and patient files. The study population, odontogenic cervico-facial cellulitis in pregnant women, included all patients with odontogenic perimandibular cellulitis during pregnancy; other locations were not included. The study parameters were age, history, contributing factors, maternal-fetal complication and treatment. Results: The study concerns five pregnant women. The average age was twenty-five years, two were carriers of HIV retrovirosis. They had all taken non-steroidal anti-inflammatory drugs, two were in the first trimester of pregnancy and three in the second trimester. All patients had diffuse perimandibular cellulitis, with cervical diffusion. Non-obstetric complications were dysphagia associated with odynophagia and obstetric complications were one threat of premature delivery. The treatment was medical-surgical. Conclusion: Odontogenic perimandibular cellulitis is more common in pregnant women in the second trimester of pregnancy. They are favored by taking non-steroidal anti-inflammatory drugs. The maternal-fetal complications found are dysphagia, odynophagia and a threat of premature delivery.