Consciousness of facial care among all age groups has become a global demand. In this scenario Toner becomes a game-changer adding formula to remove impurities, prepares the skin for next skincare steps, balances the pH levels, and restores moisture which is essential for maintaining a healthy and vibrant complexion. As our face harbours a diverse microflora regularly, such products should be tested for their antimicrobial efficacies to establish a scientific bridge. Hence, our study aimed to evaluate the antimicrobial effects of some popular toners against face isolates. For this study, bacteria were isolated from the face of ten persons and identified partially through cultural, microscopic and biochemical observations. Also the antibiotic sensitivity pattern of those face microflora was studied against different antibiotics. The isolates were resistant towards Chloramphenicol, Ampicillin, Amoxicillin, Penicillin and Cefixime, however they were found sensitive towards Kanamycin, Gentamycin, Ciprofloxacin, Tetracycline, and Azithromycin. For the key work nine numbers of most accepted toners were selected to check their antimicrobial activities against those isolates. Biotique toner showed excellent antimicrobial activity against all the isolates. Hence it is recommended to add toners to every day practices to prevail over microbial accumulation on face leading to various discomforts.