EAS Publisher | Antimicrobial Effect of Cinnamomum verum Leaf Extract on Fungus and MDR Bacteria

Antimicrobial Effect of Cinnamomum verum Leaf Extract on Fungus and MDR Bacteria

DOI : https://doi.org/10.36349/easms.2024.v07i07.001

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Multi-drug resistance is a major concern to medical science across the globe. The inability of most drugs to destroy different pathogenic bacteria and fungi demands the use of natural products like phytochemicals to treat various infections. At this juncture, Cinnamomum verum is an active agent against various bacteria and fungi. C. verum or true cinnamon is widely used as a spice. It has several medicinal values and is widely accepted as traditional medicine. Cinnamaldehyde is the most active compound of C. verum that is responsible for its antimicrobial activity. In this study, the minimum inhibitory concentration (MIC) of C. verum leaf ethanolic extract was determined against different bacteria and fungi along with ethanol as a control. The extract showed remarkable antifungal action on Candida albicans and antibacterial action against Pseudomonas aeruginosa with a MIC value of only 0.039 mg/ml. The MIC value against other microorganisms ranges from 0.78 mg/ml to 25mg/ml. C. verum leaf extract can be used as an effective antimicrobial agent in fungal and bacterial infections.

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