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Hormonal and Semen Production Response to Oral Combination of Tigernut, Soybean, Datefruit Extract and Cod Liver Oil Administration in Male Wistar Rats

DOI : https://doi.org/10.36349/easms.2024.v07i05.003
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Aim/objective: This study assess the effect of combined oral administration of tigernut, datefruit, soybean extract and liquid codliver oil on semen and hormonal indices such as sperm count, viability, ph., testosterone, FSH, LH, PSA etc using male wistar rats. Methods: The Tiet and Layman methods were used to determine the concerned hormones analyzed while the PSA and semen was calculated using calibrated curve method and hemocytometer Method. The animals were grouped into two phases. Hormonal (1) phase: This consist of 25 animals with group (1) serving as the control, (2) received 1000mg/kg soybean, (3) received 800mg/kg tigernut and datefruit, (4) 800mg/kg of combined extract of tigernut, datefruit, and soybean daily while group5 received a standard drug of 500mg/kg codliver oil daily. Phase (2) Semen analysis: This phase consist of 35 animals with group (1) also serving as control but group (2) receive 1400mg/kg tigernut, (3) receive 800mg/kg datefruit, (4) receive 1000mg/kg soybean, (5) receive 800mg/kg datefruit/tigernut, (6) receive 800mg/kg of tigernut, datefruit, and soybean extract each daily while group7 was administered 500mg/kg codliver oil daily for 35days. Results: The outcome of this study indicate an increase mean values for insulin, LH and testosterone among the test group compared with control. The FSH level was significantly higher in group2 (3.60m/u/ml) but decreases in group3 - group5 compared with the control (3.00m/u/ml) level. There was a significant positive correlation that exist between FSH and LH while the PSA levels are within normal range. Both active and sperm count were increased in percentage and in millions among group5 and group6 administered the combined extract of the fruits daily in comparison with control group. A significant increase level of testosterone and improved normal/active sperm count among the test group administered soybean extract and codliver oil daily was observed. Conclusion: This study is a break through on ..

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Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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