EAS Publisher | Harnessing Photo-Dynamic Treatment for Immune System Diseases: A Promising Therapeutic Approach: A Systematic Review

Harnessing Photo-Dynamic Treatment for Immune System Diseases: A Promising Therapeutic Approach: A Systematic Review

DOI : https://doi.org/10.36349/easjms.2024.v06i03.005

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Photodynamic treatment (PDT) has emerged as a promising therapeutic approach for immune system diseases due to its ability to selectively target abnormal cells while modulating the immune response. This review explores the mechanisms by which PDT activates the immune system to target diseased cells, including the induction of immunogenic cell death, activation of dendritic cells, release of tumor-associated antigens, modulation of immune checkpoints, and induction of cytokines and chemokines. Additionally, PDT can generate reactive oxygen species, induce apoptosis, and exhibit anti-inflammatory and vascular effects, all of which contribute to its therapeutic potential in immune system diseases [1]. Harnessing PDT for immune system diseases offers a unique opportunity to leverage the immune system's inherent ability to recognize and eliminate abnormal cells, providing a targeted and potentially less toxic treatment option. Further research and clinical studies are warranted to fully elucidate the potential of PDT in the management of immune system diseases and to optimize its clinical application.

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Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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