EAS Publisher | Biochemical Profile of People with Down syndrome: About 25 Cases

Biochemical Profile of People with Down syndrome: About 25 Cases

DOI : https://doi.org/10.36349/easjbg.2023.v05i04.001

590 Downloads 3 Views

Down syndrome or trisomy 21 is a genetic disease resulting from an additional gain of chromosome 21. It predisposes to multiple pathologies including obesity, infections, diabetes, or hypothyroidism, responsible for various biological abnormalities. This work aimed to determine biochemical profile of congolese persons with Down syndrome, living in Brazzaville (Congo). The study was carried out on 25 persons with Down syndrome. They are cared for in four specialized centers for disabled children. The methodology was based on the determination of glycaemia, proteins and lipids by spectrophotometric and electrophoretic methods. Globally, normal values of total cholesterol, triglycerides, and glucose (except for one person who had moderate hyperglycaemia), were observed. We noted an hyperlipidemia associated with low levels of HDL, LDL, albumin, and alpha 1 globulin. In Conclusion: there is a disturbance in biochemical profile in subjects with Down syndrome, which predispose to diabetes, cardiovascular diseases and opportunistic infections.

TOP EDITORS

Dr. T. Selvankumar
Chief Editor
EAS Journal of Biotechnology and Genetics

Dr. James Kay, PhD
Chief Editor
EAS Journal of Psychology and Behavioural Sciences

Dr. Rejeesh Menon
Chief Editor
EAS Journal of Medicine and Surgery

Dr. S. Jayachandran
Chief Editor
EAS Journal of Dentistry and Oral Medicine

Dr. Md. Habibur Rahman
Chief Editor
EAS Journal of Pharmacy and Pharmacology

Dr. Benard Chemwei, PhD
Chief Editor
East African Scholars Multidisciplinary Bulletin

NFI Joseph Lon
Chief Editor
EAS Journal of Humanities and Cultural Studies

Prof. Dr. Nazir Ahmad Suhail
Chief Editor
East African Scholar Journal of Engineering and Computer Sciences

Dr. Hamid Osman Hamid
Chief Editor
EAS Journals of Radiology and Imaging Technology

Dr. BOUCENNA Mounir
Chief Editor
EAS Journal of Veterinary Medical Science

OPEN ACCESS JOURNALS

Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

BEST AUTHOR

Of The Month

TRACK YOUR ARTICLE

Enter the Manuscript Reference Number (MRN)

Get Details