Background/ Objective: plants that function primarily to maintain individual health and improve the quality of life throughout the year. a traditional plant as traditional medicine is dragon tail leaves (R. pinnata (L.f.) Schott.). Therefore, this review aims to share reports and provide a comprehensive explanation of the phytochemical and pharmacological activities of (R. pinnata (L.f.) Schott.). Methods: evaluation shared facts in the literature on phytochemical activity and pharmacological activity (R. pinnata (L.f.) Schott.) through 2012-2022. Three bibliographical databases were used to obtain the main report (Pubmed, Science Direct, and Google Scholar). The keywords in this search were “Pharmacology”, “Phytochemicals”, “(R. pinnata (L.f.) Schott.)” and “Bioactive compounds”. Results: a total of 17 studies classified as this evaluation fulfilled the criteria, 8 included and 9 included pharmacological.R. pinnata (L.f.) Schott contains phenolics, alkaloids, flavonoids, tannins, triterpenoids/steroids, and saponins. A series of pharmacological studies have reported on the plant R. pinnata (L.f.) Schott has the effect of Anticancer, Anticancer breast, Antibacterial, Antimutagenic, burns, Analgesic, anti hyperuricemia, and antihyperglycemia. Conclusions: Recent interest in traditional medicine from plants R. pinnata (L.f.) Schott exhibits potential activity against pharmacological effects associated with the presence of pure bioactive compounds.