About Us   |   Contact Us   |  
Submission  

Difficulty in Diagnosing a Hemoglobinopathy: Heterozygous Beta-Thalassemia Associated with Alpha Hemoglobin Variant

DOI : https://doi.org/10.36344/ccijmb.2023.v05i01.004
PDF
HTML
XML

The diagnosis of a hemoglobinopathy is not always easy; it is based on a combination of clinical, hematological and biochemical findings, possibly including a genetic study of globin chains. Interpretation of biochemical profiles can be complicated when two hemoglobin abnormalities are associated. We report the case of a globin alpha variant associated with beta-thalassemia in a family of Moroccan origin that underwent a biological investigation. The discovery was fortuitous during the determination of HbA1c by high performance liquid chromatography. The diagnosis was confirmed by the use of complementary techniques, including capillary electrophoresis at alkaline pH and agarose gel electrophoresis at acid pH, associated with the hematological and biochemical data of the patient and his family.

TOP EDITORS

OPEN ACCESS JOURNALS

Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

BEST AUTHOR

Of The Month

TRACK YOUR ARTICLE

Enter the Manuscript Reference Number (MRN)
Get Details

Contact us


EAS Publisher (East African Scholars Publisher)
Nairobi, Kenya


Phone : +91-9365665504
Whatsapp : +91-8724002629
Email : easpublisher@gmail.com

About Us


EAS Publisher (East African Scholars Publisher) is an international scholar’s publisher for open access scientific journals in both print and online publishing from Kenya. Its aim is to provide scholars ... Read More Here

*This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2020, All Rights Reserved | SASPR Edu International Pvt. Ltd.

Developed by JM