EAS Publisher | Evaluation of Efficacy of Spirulina in Management of Oral Submucous Fibrosis

Evaluation of Efficacy of Spirulina in Management of Oral Submucous Fibrosis

DOI : https://doi.org/10.36349/easjdom.2023.v05i03.001

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Objective: Oral submucous fibrosis (OSF) is a chronic condition of the oral cavity which results in permanent disability. A number of studies have proven that the management of premalignant diseases should include antioxidants. Therefore, a study was carried out to evaluate the efficacy of spirulina in the management of 40 oral submucous fibrosis in uttar Pradesh. Materials and Method: An study was conducted on 40 oral submucous fibrosis cases, 40 patients given spirulina capsules systemetically 500 mg twice daily for period of 6 months .The results were analyzed with tukey test and ANNOVA test. Result: The result showed statistically significant improvement in burning sensation whereas it was clinically significant in mouth opening and tongue protrusion. Conclusion: Spirulina can bring about clinical improvements in OSF patients. The observed effects suggest that spirulina can be used in management of OSF patients. However, studies involving larger samples and longer period of treatment follow up are suggested in the future.

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Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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