Vaccination is one of the most efficient public health interventions in developing countries with epidemiological facies dominated by communicable diseases. Objective: To evaluate the efficiency of the logistical management of routine EPI vaccines and consumables in the Fana health district from 01 December 2018 to 30 November 2019. Results: The efficiency of the health areas in monitoring the storage temperature of vaccines (+2°c to +8°c) was 94.54%. The district obtained a rate of 100% in the management of stocks of vaccines and consumables. As for the quality of the cold chain equipment, the average rate obtained by the health district was 96.81%. The rate obtained by the district was 100% in relation to the maintenance of the cold chain equipment. In stock management, the average rate recorded in the district was 97.27%. The district obtained a rate of 100% in the efficiency of the vaccine management system. The average rate obtained by the district was 96.59% in the correct use of diluents. In the implementation of the Policy on opened vials (PFE), the rate obtained by the district was 90.81%. During the period, the management is 89.18% for the control of vaccine losses. Conclusion: All the cold chain equipment used for vaccine storage (Churchill solar fridges and vaccine carriers) comply with World Health Organization standards.