This article deals with a very old subject that is also a challenge for the medical fraternity and masses. The masses and the medical fraternity go through the hypertensive related health issues in their daily lives. The issue is clubbed as Resistant Hypertension (RH) issues which are troubling the commonest human being to that of the scientific community. While the modern medicine through the existing treatment deals with the problem with chemical medications for the circulatory system, this article focuses on Homoeopathic system of medicine. Homoeopathy is clinically effective, cost effective and has no side effects. As all the homoeopathic medicines go through human clinical trial or are proved on human beings, all medicines have a mental calming aspect during the trials. This shows that there are N numbers of medicines in homoeopathy for the RH issues also. The current piece deals with some of the leading medicines based on the clinical experience of the lead author. Readers are requested to adhere to the protocol discussed here. The reader will get an idea of the problem at global & national level through the eyes of clinical health in the beginning sections before delving in to the Homoeopathic system of the AYUSH platform. Currently, the AYUSH platform has regained its value in the era of the current pandemic. The pandemic has escalated the RH issues further. In the absence of effective therapy in the modern medicine, the article peeps through what homoeopathy can offer to deal with RH issues that are effective clinically, safe and without side effects.