Abstract: The major advantage of using plant extracts for silver nanoparticle synthesis is that they are easily available, safe, and nontoxic in most cases, have a broad variety of metabolites that can aid in the reduction of silver ions, and are quicker than microbes in the synthesis. The main mechanism considered for the process is plant-assisted reduction due to phytochemicals. In present we had selected two plant - Ziziphus mauritina commonly known as Indian jujube (Ber) and Coriandrum sativum commonly known as coriander for the phytochemical screening, nanoparticle synthesis and antibacterial activity against Kliebsella pneumonia, Clostridium per fringes, Citrobacter freundii and Staphylococcus aureus bacteria. All the bacteria selected in this study are highly and drug resistant. Potency of these plant extract against selected bacterial culture increases with formulation of nanoparticles .When compared with free extract in terms of zone of inhibition exhibited by bacterial culture. Zeta potential analysis of nanoparticles confirms that all the nanoparticles are of size loss them 100 nm. Stability of nanoparticles up to 15 days was observed which confirms the method of preparation of nanoparticle is stable and successful. Research finding confirms the format and stable nature of nanoparticles, which make them, potential and significant in drug delivery agent.