Background: Maintaining one's professional competence in today's quickly evolving environment is essential, and it is crucial that nurses at all levels of the healthcare system demonstrate an interest in continuing professional education that lasts a nurse's whole career. Purpose: The purpose of this study was to determine factors motivating nurses’ participation in continuous professional development in Kenya. Methodology: A cross sectional descriptive study was conducted in Narok County Referral hospital. A mixed method approach, which provided for triangulation that sought convergence and corroboration of the results from questionnaire, was adopted. Purposive sampling was used to recruit 40 respondents for the study. Data was checked for completeness and consistency and then entered into SPSS version 26.0 for analysis. Descriptive statistics used included frequencies, percentage, mean and standard deviation. Findings: Results of the mean and standard deviation revealed that majority of the respondents agreed that career development prospect had motivated them to participate in continuous professional development (M =4.15, SD =0.802). Similarly, the respondents were of the view that they participated in continuous professional development in order to keep themselves up to date with the constant changes in the nursing profession (M =4.40, SD =0.810). Upgrade skills and knowledge and to increase professionalism was another factor that motivated nurses to participate in continuous professional development as depicted by the mean and standard deviation (M = 4.30, SD = 0.939). Conclusion: Due to the complexity of the health care system, nurses are required to remain relevant in their area of practice. Continuous professional development equips the nurse with knowledge and skills to perform nursing care professionally. The critical component in achieving favorable results for quality patient’s nursing care is achieved by lifelong learning through continuing professional