Introduction – The hormonal changes in postmenopausal women could affect their physical and psychosocial conditions. Moreover, it can influence the quality of life among postmenopausal women. The study aimed to describe the quality of life among Indonesian postmenopausal women. Method – The study was applied descriptive design with a cross-sectional approach. The sample was selected using consecutive technique sampling. The inclusion criteria were post-menopause women who willing to participate in this study and physiological menopause. The exclusion criteria were post-menopause women with severe illness (i.e. cancer, autoimmune diseases, bone diseases, thyroid dysfunction), and under steroid treatment. The demographic and Menopause-Specific Quality of Life (MENQOL) questionnaire were used to gathering the data. The descriptive analysis was used to answer the study questions. Results – Forty-one postmenopausal women participated in this study. The mean age was 66.76 years old (SD ± 8.89), age of menarche was 13.88 (SD ± 1.74) and the age of menopause was 50.85 (SD ± 4.40). The mean of the MENQOL dimensions were vasomotor (1.71, SD = 1.08), psychosocial (1.93, SD = 0.65), physical (2.32, SD = 0.09), and sexual (2.54, SD = 0.87). Most postmenopausal women experience complaints on three of four dimensions of MENQOL i.e. psychosocial, physical, and sexual dimensions. Discussion – Responsibility as a woman was influence the complaints among postmenopausal women. The climate and duration of menopause were associated with the vasomotor complaint. For another reason, educational level, occupation, and marital status were influenced by psychosocial, physical, and sexual dimensions