Background: A novel corona virus disease (COVID-19) has spread rapidly around the world since it was first identified in January 2020 in Wuhan in Republic of China. WHO declared that corona virus was public health emergency in 30th of January 2020. In 11th of March WHO declared COVAID-19 as a pandemic disease, Ministry of health in Sudan announced the first case on the 12th of March 2020. Objective: This study was conducted to assess awareness of the Sudanese population regarding COVID-19. Methods: It was descriptive cross-sectional community based study. The data was gathered from 385 participants from different locality in Khartoum state, Sudan using electronic questionnaire developed by the researchers at Google form document then analyzed by SPSS version 25 and the results were displaced in frequency and percentage. The level of statistical significance was set at p = 0.001. Results: The finding regarding basic knowledge of the participants revealed that the majority of the participants (98.2%) were aware that the disease was a viral illness in it is nature, most of the participants reported accurate and correct information about the mode of transmission. (92.7%) believed that contaminated surfaces were modes of transmission, while 86% stated that droplet was a mode of transmission with virus. Regarding signs and symptoms of COVID-19 the majority of the participants showed high percentage of awareness (fever 95.3%, sore throat 89.1%, headache 88.6%, dry cough, 89.1%, and shortness of breath 89.6%). Regarding methods of protection of coV-19 most of participants (85%) said that they were doing hand washing, wearing masks and practicing social isolation, (98.4%) believed that there was no vaccination. Only (16.9%) of the participants believed there was no specific treatment, but 44% said symptoms can treated by anti-malarial drugs. Regarding respiratory etiquette, (89.4%) were using the inner side of the elbow while sneezing, (65.7%) were taking full precautions w