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A Meta-Analysis of Randomized Controlled Trials comparing the effect of intraoperative methadone to morphine on postoperative pain

DOI : https://doi.org/10.36349/easjacc.2020.v02i06.002
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Introduction: Despite recent developments in postoperative pain management, many patients still suffer from moderate-to-severe pain after surgery. It is estimated that postoperative severe pain occurs in 20%–40% of all surgical procedures. Pain during the first days after surgery might lead to severe complications, such as delayed ambulation, increased incidence of cardiovascular and pulmonary complications with increased morbidity and mortality, and the development of chronic postoperative pain. Therefore, the proper treatment of postoperative pain is of great importance, especially in procedures that lead to severe pain.

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Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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