Introduction: The health discipline is very important for maintaining the health and living standards of the population. Health unit management is one of the factors contributing to the quality of health services provided, increasing both citizens’ and job satisfaction. Purpose: The purpose of this review study is to present a high-tech management information system in a healthcare unit; and in particular, a hospital emergency department. It will also present the functional and non-fictional needs of the system, its possible solutions and its evaluation. Methodology: Greek and international scientific databases were reviewed. The study material consisted of articles on the topic found in Greek and international databases such as: Google Scholar, Mednet, Pubmed, Medline and the Hellenic Academic Libraries Association (HEAL-Link). Results: The major difficulties commonly encountered in health units are patient management and quality of health services provided. In particular, the health discipline is particularly sensitive and it is characterized by diversity. There are also many specialties in that sector that require cooperation amongst doctors, nurses, administration officials, providers and other specialties. Problems such as reduction in health expenditure have recently led to a reduction in available resources and staff in health facilities. Conclusions: There are many information systems that can be used in a hospital department that should be studied by both specialists and staff.