EAS Publisher | Seronegative Primary Biliary Cholangitis: Epidemiological, Clinical, Therapeutic and Progressive Features

Seronegative Primary Biliary Cholangitis: Epidemiological, Clinical, Therapeutic and Progressive Features

DOI : https://doi.org/10.36344/ccijmb.2020.v02i09.003

767 Downloads 2 Views

Introduction: Seronegative PBC (specific AMA antibodies are negative) is a particular clinical form of PBC.The aim of this study was to determine the clinical-biological and evolutionary features of seronegative PBCs. Methods: The medical data of 42 PBC patients were evaluated and the AMA positive and negative groups were compared. Results: 42 cases of PBC were collected. These were 41 women and 1 man. The mean age at diagnosis was 46 years (25-70 years). AMA Abs were most often positive (n = 34). Other antibodies were found in 22 patients. In our series, 9.75% of cases had seronegative PBC. By comparing the 2 groups of PBC with or without AMA Abs, depending on age, sex, degree of fibrosis and response to AUDC, no statistically significant difference was noted. Conclusion: In our series, the prevalence of seronegative PBC was 9.75%. Its clinical-biological and evolutionary profile under treatment does not seem to differ from that of seropositive PBC.

TOP EDITORS

Dr. T. Selvankumar
Chief Editor
EAS Journal of Biotechnology and Genetics

Dr. James Kay, PhD
Chief Editor
EAS Journal of Psychology and Behavioural Sciences

Dr. Rejeesh Menon
Chief Editor
EAS Journal of Medicine and Surgery

Dr. S. Jayachandran
Chief Editor
EAS Journal of Dentistry and Oral Medicine

Dr. Md. Habibur Rahman
Chief Editor
EAS Journal of Pharmacy and Pharmacology

Dr. Benard Chemwei, PhD
Chief Editor
East African Scholars Multidisciplinary Bulletin

NFI Joseph Lon
Chief Editor
EAS Journal of Humanities and Cultural Studies

Prof. Dr. Nazir Ahmad Suhail
Chief Editor
East African Scholar Journal of Engineering and Computer Sciences

Dr. Hamid Osman Hamid
Chief Editor
EAS Journals of Radiology and Imaging Technology

Dr. BOUCENNA Mounir
Chief Editor
EAS Journal of Veterinary Medical Science

OPEN ACCESS JOURNALS

Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

BEST AUTHOR

Of The Month

TRACK YOUR ARTICLE

Enter the Manuscript Reference Number (MRN)

Get Details