Unless and until a proper solution is made and adopted in the health care delivery systems throughout the world to combat COVID-19, some experimental drugs are employed everywhere on the globe in the management of COVID-19. Number of times chemical drugs have proven fatal as well, unfortunate part is “drug induced fatalities” if we are not wrong these fatalities are included in the number of deaths due to COVID-19. The need of the hour is to reduce morbidity and mortality from COVID-19/ COVID-19 drugs. Our motive is to design a formulation which can not only provide the symptomatic relief but will act as anti-retroviral and at the same time will be safe for oral administration. This review paper is based on the same ideology. We have designed a decoction, a diet module and a formulation for inhalation with scientific evidences. That is why we choose only those herbs in formulation which are strongly anti-retroviral. The herbs with weak potency were excluded otherwise there are more than seventy-five herbal drugs with similar actions. Many times, we need booster doses when virus is quantitively or qualitatively more virulent that is why we have given emphasis to the anti-retroviral diet so that the better result is achieved. The purpose of inhalation is the Nano particles of herbs shall reach easily to the target tissues.