This study aimed at cockroach infestations and their perceived importance in disease transmission was carried out in Yenagoa metropolis of Bayelsa State of Nigeria using sample survey method involving the retrieval of 225 descriptive questionnaires from the people bound on their knowledge of cockroach as vector of pathogenic organisms and the possible modes of control. On the frequency of cockroach infestation in habitats, respondents reported 20.40% cockroach infestation in private homes, schools (7.80%), offices (5.90%), hospitals (12.20%), toilets (18.40%), dust bins (15.70%) and restaurants (19.60%). 82.4% of the respondents affirmed that cockroaches are carriers of disease pathogens and are implicated as causative organisms of allergies and respiratory disease. About 23.5% were well aware that cockroach infestation triggers asthmatic attack in sensitive people. All the surveyed houses reported cockroach infestation, with high prevalence in the older houses (71.40%) compared to the recently built ones (53.90%). 78.4% of the respondents gave poor sanitary condition as an indicator for high cockroach prevalence. Concerning best method of control, 54.90% voted for the use of synthetic pesticides, biological control (23.53%) and cultural control (21.57%). Therefore, the teeming populace of Bayelsa State should be educated as to the perceived importance of the prevalence of cockroaches in homes, hospitals and food preparation centers especially as vectors of pathogenic organisms and be further sensitized on the best control practices such as good sanitation practice, food hygiene, stocking foodstuffs in sealed containers and proper disposal of refuse so as to reduce cockroach related menace.