Introduction: Congenital diaphragmatic hernia (HDV) is a rare malformation. The posterolateral or Bochdalek form is the most frequent (80%) and is located on the right in only 15% of cases. It is a rare cause of respiratory distress in newborns. Our objective was to describe the diagnostic and therapeutic aspect of a case in a 10-day-old newborn in the neonatology unit of the Mali hospital. Observation: He was a 10-day-old male infant admitted for dyspnea from birth. He was born from a pregnancy followed to term without major incidents. Syphilis serology was negative. However, toxoplasmosis, rubella, hepatitis B and HIV serologies have not been performed. Four ultrasounds performed during pregnancy returned to normal. He was born by scheduled Cesarean section uterus and resuscitated at birth. The emergency chest X-ray was not informative. The diagnosis of right congenital diaphragmatic hernia was confirmed by the thoracoabdominal CT scan. A treatment combining oxygen therapy, 10% glucose serum: 100 ml / kg / d in infusion and domperidone: 1 ml / kg / d in 3 administrations per os has been established. After one month and 23 days of hospitalization, after stabilization of respiratory distress, he was operated. The aftermath was simple. Conclusion: Congenital diaphragmatic hernia is a rare condition. The posterolateral form is more common. Respiratory distress is their main mode of revelation at birth. In the event of any neonatal respiratory distress, the hypothesis of HDC must be evoked and confirmed by an X-ray of the chest.