Introduction: The study of mortality makes it possible to control and revise therapeutic measures in a health facility. Maternal death is a major concern in the world, it is a social tragedy. We present a study on maternal death at the Mother Child Health Center in the Zinder region. Methodology: The study was a retrospective, descriptive study covering eleven months from January 1st to November 30th, 2017. Study conducted at the mother and child health center in the Zinder region, the main regional reference point for obstetric gynecology. The objective was to determine the epidemiological profile of deceased parturients. Patients admitted directly or evacuated from other health facilities and who died as a result of maternity were included. Patients who died outside the gestational setting were excluded. Data was collected from the admission register, the maternal death audit report and the patient record. The variables studied were epidemiological data, type of anesthesia, ASA class, cause of death, mode of transport. Results: A total of 10090 patients admitted were studied, one hundred and sixteen (116) women died (1.14%) and 3030 deliveries was conducted, of which 2635 were live births. The average age was 26.28 years with extremes of 15 years and 42 years. The 21 to 30 age group was the most affected with 31.89% (n = 37). Large multiparas (5 to 13 parities) were in the majority with 46.55% (n = 54). Transportation was unsafe at 86.20% (n = 100) and 68.96% (n = 80) was more than 50 km from the site of care. Almost all, 99.13% (n = 115) were uneducated and unprofessional. NPC was not achieved in 98.27% (n = 114) of the cases. Anesthesia was performed in 23.27% (n = 27) of the patients including 19.82% general anesthesia and 03.44% spinal anesthesia. The ASA I class represented 14.81% (n = 04), ASA II 74.07% (n = 20) and 11.11% for the other classes. The midwife was the caregiver in 87.93% (n = 103) of the cases. Delayed treatment was the leading cause of .......