EAS Publisher | Profile of Congenital Heart Anomalies in Children with Down’s Syndrome

Profile of Congenital Heart Anomalies in Children with Down’s Syndrome

DOI : https://doi.org/10.36349/easms.2021.v04i09.001

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Background: Down’s syndrome (DS) is one of the commonest chromosomal disorder and congenital heart disease (CHD) is consider as the most important malformation of DS with an incidence of 40 to 60%. Pattern of CHD in DS have wide variation and is responsible for a significant number of mortality as well as morbidity in children specially during first year of life. Materials and Methods: It was a Prospective, observational single center study done over a period of one year from January’ 2020 to December’ 2020. Chromosomal study and Echocardiography done to all children after admission. Results: Of the 98 study children 51 had congenital heart disease (52.04%), among them ostium secundum atrial septal defect was the commonest one (31.37). Conclusion: There is very high incidence of CHD among Down’s syndrome (DS) children, and it was 52.04% in this study. Early cardiac evaluation of DS children is of paramount importance for appropriate management plan and timely intervention in order to reduce mortality and morbidity of patients with CHD in Down’s syndrome.

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