Objective: To determine the frequency of primary infertility in women suffering from fibroid uterus. Study Design: Cross-sectional study. Setting and Duration: Outpatient department of gynecology and obstetrics of Bolan Medical Complex Hospital Quetta from 1st Jan 2018 to 30th Jun 2018. Sample size: The calculated sample size is 203 patients, with 95% confidence level and absolute precision of 3%, taking percentage of infertility 5% with fibroid uterus. Sampling technique: Non-probability consecutive sampling. Results: A total of two hundred and three women presented with fibroid uterus were selected during study period through out patient department of Bolan Medical Complex Hospital Quetta. 12.8% were between 18-25 years, 45.3% were between 26-32 years and 41.9% were between 33 to 40 years of age. Out of 203 patients only 9.9% had infertility, and remaining 90.1% were enjoying healthy reproductive life. In 63% cases there were multiple and in 36.9% of cases were single fibroids. Conclusion: In our study only 9.9% patients with fibroid uterus had primary infertility. The remaining patients had no issue with conception having fibroids. Having fibroid uterus may be only one reason of infertility, many other aspects need to be considered while treating infertility.