COVID-19 which is caused by SARS-CoV-2 is among the severe respiratory disease to be witnessed to date. SARS-Cov-2 brought about therapeutic and preventive difficulties all over the globe. The aim of this review is to evaluate the best possible therapeutic options to tackle the Novel Coronavirus related disease. We extracted relevant published studies with keywords such as COVID-19 therapies, Sars-Cov-2 treatment and Noval Coronavirus antiviral therapy from Pubmed and carefully studied them. We focused on Tocilizumab, chloroquine and hydroxychloroquine, Lopinavir/Ritonavir, Remdesivir, Traditional Chinese Medicine and Ivermectin. Coronavirus induce Cytokines Releasing Syndrome (CRS) which in turn causes Cytokines Storm. This is the inflammatory response which causes the releasing of large number of IL-6. This causes increased vascular permeability which in turn result in the infiltration of fluids in the alveolar spaces and causes breathing problems. Tocilizumab can block the inflammatory response induced by SARS-CoV-2 infection and hence prevent the vascular permeability which in turn prevents the pulmonary edema and Disseminated Intravascular Coagulation (DIC) and hence prevent respiratory failure. Remdesivir which is an adenosine nucleotide analogue, has broad-spectrum antiviral activity against RNA Viruses. This means remdesivir can prevent the viral replication and hence lower the viral load and ultimately reduce the duration of illness and hospitalization. Ivermectin which is FDA approved broad spectrum antiparasitic agent, works by preventing the entrance of viral protein in the host cell nucleus. Ivermectin binds to the viral protein transporters Importin (IMP) α and β1. This action prevents the binding of the viral protein to the Importin (IMP) which results in the lower infection rate and decreased viral load. Lower rate of infection and decreased viral load will reduce duration of illness and prevent transmission of SARS-CoV-2. So, the concomitant .......