EAS Publisher | Liposomes for the Drug Delivery: A Review

Liposomes for the Drug Delivery: A Review

DOI : https://doi.org/10.36349/easjpp.2021.v03i05.003

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Formulation of drugs in liposomes has provided an opportunity to enhance the therapeutic indices of various agents mainly through alteration in their bio distribution. Liposomes are a novel drug delivery system (NDDS), they are vesicular structures consisting of bilayer which form spontaneously when phospholipids are dispersed in water. They are microscopic vesicles in which an aqueous volume is entirely enclosed by a membrane composed of lipid bilayers. The goal of any drug delivery system is spatial placement and temporal delivery of the medicament. Research works are going on to prepare an ideal drug delivery system which satisfies these needs. Liposomes are small vesicles (100 nm) composed various lipid molecules which build their membrane bilayers. These formulations are mainly composed of phosphatidylcholine and other constituents such as cholesterol and lipid-conjugated hydrophilic polymers. Liposomes are biodegradable and biocompatible in nature.

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